39-year-old woman with multiple pigmented lesions over an 8-year period

    The patient presented with a pigmented lesion on her right ankle in 2002, at the age of 39 years.  A biopsy showed malignant melanoma, surperficial spreading type, with an intraepidermal component.  Over the course of the next eight years she developed three additional pigmented lesions on the right lower extremity, proximal to the original lesion, which were also biopsied.  Photomicrographs of all four lesions are shown, from the most recent to the original lesion.