David E. Elder, M.D.

    Dr. David Elder is Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania, the teaching hospital of the oldest medical school in the United States. He trained in New Zealand at the University of Otago and with Dr. Vincent McGovern of the Sydney Melanoma Unit in Australia. He then moved to Philadelphia, initially with Dr Wallace H Clark Jr. at Temple University and then at the University of Pennsylvania. Dr. Elder was Vice Chair for Anatomic Pathology in the Department of Pathology and Laboratory Medicine from 1999 through 2011, and was a founding member of the Penn Melanoma and Pigmented Lesion Study Group in 1978, and the Melanoma Program of the Abramson Cancer Institute at the Perelman School of Medicine at the University of Pennsylvania. Over the years, this group described dysplastic nevi, and defined the radial and vertical growth phases of melanoma. In other studies, prognostic models for melanoma were developed, using histopathologic and other markers. These have included proliferation markers, and markers of the tumor host response. The group has also been closely involved with the development of new targeted therapies and of immunotherapy for melanoma. This work has been funded by NIH Program Project and multidisciplinary SPORE grants in which Dr. Elder has been PI of Projects and Pathology Cores. Dr. Elder has also been a leading member of the Melanoma Genetics Consortium (GenoMel), serving as Principal Investigator of an NIH grant supporting this program over the last two decades and more. This group has defined the biology of genes that convey risk for the development of melanoma in Europe, Australia and the Americas. Dr. Elder is the author of more than 200 peer-reviewed research publications and reviews. In addition, he has authored or edited several textbooks, including the 3rd and 4th series US Armed Forces Institute of Pathology Fascicles on Melanocytic Tumors of the Skin, and he has also been Editor in Chief for the last four editions of Lever’s Histopathology of the Skin, a book that has been continuously published since 1948 and is a leading textbook in the field of dermatopathology. Another publication is the Atlas and Synopsis of Lever’s Histopathology of the Skin, now in its third edition, which presents a unified pattern classification system for inflammatory and neoplastic skin diseases. He is also Series Editor of Consultant Pathology, a series of monographs whose aim is to convey the nuances of pathology diagnosis as practiced by leading consultants in their respective fields. Dr Elder continues to pursue his interests in the classification and diagnosis of skin disease and in particular the diagnosis and prognosis of melanoma and other melanocytic tumors.