Atopic dermatitis

    Article Contributors: 
    Sean Klepper M.D.
    Stephen Lyle, M.D., ...

    Clinical Features:

    • Often begins in infancy or early childhood, with a female predominance
    • Associated with asthma and allergic disorders
    • Presents with pruritus, erythema, scaling, excoriation, lichenification and superimposed lichen simplex chronicus
    • In young children, most often affects the face and extensor surfaces of the extremities
    • In older children and adults, flexural surfaces and neck are most commonly involved.

    Histologic Features:

    • Mild to moderate subacute to chronic spongiotic dermatitis
    • Eosinophils and Langerhans cell clusters are absent, in contrast to allergic contact dermatitis.
    • Follicular involvement is common.
    • Due to the intense pruritus, the lesions are often rubbed or scratched, and secondary lichen simplex chronicus develops.

    External Links:


    Cases associated with this book:

  • Atopic dermatitis
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: Teaching Collection