Fibrous hamartoma of infancy

    Clinical Features:

    • Benign tumor presenting in the first two years of life
    • Male predominance
    • Solitary dermal and subcutaneous mass, most commonly on the shoulder, proximal upper limb, groin, back or forearm
    • Presents as a firm, mobile sesion up to 10 cm in diameter
    • May rarely recur if incompletely excised

    Histologic Features:

    • Ill-defined lesion mainly within the deep dermis and subcutis, composed of varying amounts of:
      • Disordered fibrous tissue: coarse collagen bundles with blood vessels and inflammation
      • Fascicles of myofibroblasts
      • Mature adipose tissue
      • Foci of myxoid tissue containing primitive mesenchymal cells with a whorled configuration
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    Cases associated with this book:

  • Fibrous hamartoma of infancy
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: Teaching Collection