Fibrous papule of the nose

    Clinical Features:

    • Commonly presents on the face of middle-aged individuals, with a predilection for the nose
    • Small skin-colored papule

    Histologic Features:

    • Slightly raised
    • Well-circumscribed upper dermal lesion composed of collagenous stroma with increased vascularity and scattered spindled and/or mutinucleated cells
    • Variants with granular or clear cell change exist.
    • The epidermis is normal to slightly atrophic.
    • The lesional cells stain for factor XIIIA and sometimes CD34.  They are negative for S-100.
    External Links:

    Cases associated with this book:

  • Fibrous papule
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: Teaching Collection