Pityriasis rubra pilaris

    Article Contributors: 
    Sean Klepper M.D.
    Artur Zembowicz M.D....

    Clinical Features:

    • Autosomal dominant familial and sporadic forms
    • Large scaly plaques with islands of sparing, most often on the trunk
    • Hyperkeratosis of the palms and soles and nail dystrophy may occur.

    Histologic Features:

    • Hyperkeratosis with horizontally and vertically alternating foci of parakeratosis (described as a "checkerboard" pattern)
    • Mounds of parakeratosis at the edges of follicular ostia ("shoulder parakeratosis")
    • Keratotic plugging of the follicular ostia
    • Irregular to psoriasiform acanthosis with hypergranulosis and occasionally acantholysis
    • Mild superficial perivascular lymphocytic infiltrate
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    Cases associated with this book:

  • Pityriasis rubra pilaris
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection