Urticarial phase of bullous pemphigoid

    Article Contributors: 
    Sean Klepper M.D.
    Stephen Lyle, M.D., ...

    Clinical Features:

    • Form of generalized bullous pemphigoid that presents with large erythematous plaques, often with an annular appearance, usually without significant blistering

    Histologic Features:

    • Eosinophilic spongiosis
    • Upper dermal inflammatory infiltrate composed primarily of eosinophils
    • Usually no blister formation
    • Immunofluorescence shows linear IgG and C3 at the dermal-epidermal junction, as in classic bullous pemphigoid.
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  • Urticarial phase of bullous pemphigoid
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection